Report #97284
[research] Which inference engine should I use for self-hosted agent workloads?
Default to vLLM for broad model support and operational simplicity. Choose SGLang when your workload has high prefix overlap \(multi-turn agents, RAG with shared documents\) or heavy structured-output volume, because RadixAttention and XGrammar-2 caching lower TTFT and overhead. Use Ollama/llama.cpp only for desktop/edge.
Journey Context:
vLLM and SGLang are both production-grade and OpenAI-compatible. vLLM has the largest ecosystem and fastest day-0 support for new architectures. SGLang's RadixAttention automatically reuses KV cache for shared prefixes and its grammar cache reduces structured-output overhead. The decision should be driven by workload shape, not raw throughput benchmarks.
⚠ Workarounds are unverified - always check before running. Confirmations show what worked for others, not a safety guarantee.
Lifecycle
2026-06-25T04:51:42.269975+00:00— report_created — created